Tell your care team if your symptoms do not start to get better or if they get worse. information is beneficial, we may combine your email and website usage information with If you are pregnant or may be pregnant. Arnica: What It Is and How To Use It Cleveland Clinic Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. diclofenac Diclofenac Sodium Gel 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). Diclofenac Sodium Topical: Uses, Side Effects, Interactions Will they also harm your kidneys? Get useful, helpful and relevant health + wellness information, 9500 Euclid Avenue, Cleveland, Ohio 44195 |, Important Updates + Notice of Vendor Data Event, Coronary artery bypass graft (CABG) within the past 2 weeks, Receiving steroids like dexamethasone or prednisone, Take medications that treat or prevent blood clots, An unusual or allergic reaction to diclofenac, other medications, foods, dyes, or preservatives, Medications that treat or prevent blood clots like warfarin, enoxaparin, and dalteparin, NSAIDs, medications for pain and inflammation, like ibuprofen or naproxen, Steroid medications like prednisone or cortisone, Allergic reactionsskin rash, itching, hives, swelling of the face, lips, tongue, or throat, Bleedingbloody or black, tar-like stools, vomiting blood or brown material that looks like coffee grounds, red or dark brown urine, small red or purple spots on skin, unusual bruising or bleeding, Heart attackpain or tightness in the chest, shoulders, arms, or jaw, nausea, shortness of breath, cold or clammy skin, feeling faint or lightheaded, Heart failureshortness of breath, swelling of ankles, feet, or hands, sudden weight gain, unusual weakness or fatigue, Kidney injurydecrease in the amount of urine, swelling of the ankles, hands, or feet, Liver injuryright upper belly pain, loss of appetite, nausea, light-colored stool, dark yellow or brown urine, yellowing skin or eyes, unusual weakness or fatigue, Redness, blistering, peeling, or loosening of the skin, including inside the mouth, Strokesudden numbness or weakness of the face, arm, or leg, trouble speaking, confusion, trouble walking, loss of balance or coordination, dizziness, severe headache, change in vision. WebTo prevent gastrointestinal (GI) adverse effects associated with the use of a nonsteroidal anti-inflammatory drug (NSAID): Avoid prescribing more than one NSAID at a time. Discuss the risks and benefits with your doctor or pharmacist. They can happen weeks to months after starting the medication. You can apply this gel to your skin as directed on the affected area of your body. Policy. You may report side effects to the FDA at 1-800-FDA-1088. Diclofenac topical may also cause stomach or intestinal bleeding, which can be fatal. The nephrologist believes his kidney deterioration was caused by taking Aleve (naproxen) for arthritis pain for many years.. Diclofenac (Oral Route) Side Effects - Mayo Clinic Do not use cosmetics, sunscreen, lotions, insect repellant, or other medicated skin products on the same area you treat with diclofenac topical. Check with your doctor immediately if any of the following side effects occur: Get emergency help immediately if any of the following symptoms of overdose occur: Some side effects may occur that usually do not need medical attention. information and will only use or disclose that information as set forth in our notice of decrease in urine output or decrease in urine-concentrating ability, stomach bloating, burning, cramping, discomfort, upset, or pain, sores, ulcers, or white spots on the lips or in the mouth, vomiting of blood or material that looks like coffee grounds, Blistering, peeling, loosening of the skin, burning, crawling, itching, numbness, prickling, "pins and needles" , or tingling feelings, dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position, feeling of constant movement of self or surroundings, pain or discomfort in the arms, jaw, back, or neck, red skin lesions, often with a purple center, shakiness in the legs, arms, hands, or feet, trembling or shaking of the hands or feet, change in the ability to see colors, especially blue or yellow, irregular, fast or slow, or shallow breathing, pain or discomfort in the chest, upper stomach, or throat, puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue, unusual drowsiness, dullness, or feeling of sluggishness, continuing ringing or buzzing or other unexplained noise in the ears, excess air or gas in the stomach or intestines, increased sensitivity of the skin to sunlight, redness, pain, swelling of the eye, eyelid, or inner lining of eyelid, redness or other discoloration of the skin. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. the unsubscribe link in the e-mail. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. However, topicals may not work well for hip pain, because the joint is too deep for the medication to penetrate. My doctor prescribed diclofenac gel for a muscle injury. Diclofenac topical may also be used for purposes not listed in this medication guide. information highlighted below and resubmit the form. Diclofenac (Topical Application Route) Side Effects Limit your time in the sun. This is not a complete list of side effects and others may occur. other information we have about you. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. The presence of other medical problems may affect the use of this medicine. Drug class: Topical non-steroidal anti-inflammatories. This medicine may cause a delay in ovulation for women and may affect their ability to have children. You may also need to avoid Symptoms of overdose may include: severe stomach pain, change in the amount of urine, slow/shallow breathing. This is more likely if you have had a stomach ulcer in the past, if you smoke or drink alcohol regularly, are over 60 years of age, are in poor health, or are using certain medicines (eg, steroid medicine, blood thinner). pharmacist if you have questions about the best way to throw out drugs. However, elderly patients are more likely to have age-related kidney, heart, or stomach problems, which may require caution and an adjustment in the dose for patients receiving diclofenac topical. This medication may raise your blood pressure. Do not get it in your eyes. Safe and appropriate use of diclofenac in chronic kidney - PubMed 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. A gel form of the prescription NSAID diclofenac ( Voltaren Gel) is one option. This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions. Weakness on 1 side of the body, trouble speaking or thinking, change in balance, drooping on one side of the face, or blurred eyesight. Tell your doctor about all your current medicines, especially: a blood thinner (warfarin, Coumadin, Jantoven); heart or blood pressure medication, including a diuretic or "water pill"; or. Talk with the doctor. Mayo Clinic does not endorse companies or products. This medicine may cause a serious allergic reaction called anaphylaxis, which can be life-threatening and requires immediate medical attention. Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Empty the contents of the packet into a cup with 1 to 2 ounces (30 to 60 milliliters [mL]) of water. The Dangers of Diclofenac and Other NSAID Pain Stop using diclofenac and seek medical treatment if you have a serious drug reaction that can affect many parts of your body. Things to remember when you fill your prescription. A very serious allergic reaction to this drug is rare. Diclofenac If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. 2005 - 2023 WebMD LLC, an Internet Brands company. Also call your doctor at once if you have: severe headache, blurred vision, pounding in your neck or ears; liver problems--nausea, diarrhea, stomach pain (upper right side), tiredness, itching, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); low red blood cells (anemia)--pale skin, unusual tiredness, feeling light-headed or short of breath, cold hands and feet; or. Several weeks may pass before you feel the full effects of this medicine. Topical non-steroidal anti-inflammatories, Detailed Diclofenac topical dosage information, Drug class: topical non-steroidal anti-inflammatories. Check with your doctor immediately if any of the following side effects occur: Get emergency help immediately if any of the following symptoms of overdose occur: Some side effects may occur that usually do not need medical attention. Adults and children 12 years of age and older25 milligrams (mg) 4 times a day. Make your tax-deductible gift and be a part of the cutting-edge research and care that's changing medicine. This is not a list of all drugs or health problems that interact with diclofenac gel (1%). In other words, the FDA makes little distinction between the dangers of diclofenac gel topical formulation and oral diclofenac. Diclofenac topical can increase your risk of fatal heart attack or stroke. Data sources include IBM Watson Micromedex (updated 5 June 2023), Cerner Multum (updated 25 June 2023), ASHP (updated 11 June 2023) and others. A. Nonsteroidal anti-inflammatory drugs (NSAIDs) like diclofenac, ibuprofen or naproxen can be hard on the kidneys. Call your care team right away if you have stomach pain or blood in your vomit or stool. To reduce your risk of side effects, use this medication at the lowest effective dose for the shortest possible time. Your condition may get worse when exposed to the sun. It should not be allowed to come in contact with the eyes. To help you remember, use it at the same times each day. other information we have about you. Heart surgery (eg, coronary artery bypass graft [CABG] surgery)Should not be used to relieve pain right before or after the surgery. Rash, scaling, dry skin, swelling, or itching may occur at the application site. Avoid getting diclofenac topical in your eyes. You'll soon start receiving the latest Mayo Clinic health information you requested in your inbox. In these cases, your doctor may want to change the dose, or other precautions may be necessary. In people who already have heart failure, the chance of heart Topical nonsteroidal anti-inflammatory drugs (NSAIDs) can bring weeks of pain relief. For this medicine, the following should be considered: Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Solaraze is used to treat warty overgrowths of skin (actinic keratoses) on sun-exposed areas of the body. If you have asthma, talk with your doctor. Wash and dry your hands before applying the medication. Do not take diclofenac gel (1%) by mouth. Put on a missed dose as soon as you think about it. Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Diclofenac topical can increase your risk of fatal heart attack or stroke, even if you don't have any risk factors. Q. I am especially sensitive to NSAIDs because of impaired kidney function. Store in a dry place. Use the lowest dose that is effective in treating your condition. Do not keep outdated medicine or medicine no longer needed. This medication may harm an unborn baby and cause problems with normal labor/delivery. Check with your doctor right away if you have stomach pain, confusion, difficulty with breathing, irregular heartbeat, nausea or vomiting, nervousness, numbness or tingling in the hands, feet, or lips, or weakness or heaviness of the legs. My nephrologist and urologist said nothing could be done. Read it with care. Facebook Twitter Mayo Clinic does not endorse companies or products. The Effect of Diclofenac Sodium on Renal Function If you notice any other effects, check with your healthcare professional. Call your doctor right away if you have signs of Talk to your care team about the use of this medication in children. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Sometimes, this has been deadly. Do not put on 2 doses at the same time or extra doses. The incidence of application-site reactions in this study (29.0%) was greater than in recent studies of diclofenac sodium gel (5%6% incidence) 22, 23 but was similar to that observed in previous placebo-controlled trials of diclofenac topical solution. That makes topical NSAIDs less risky than oral NSAIDs, which can cause stomach ulcers and bleeding, liver and kidney damage, and increased risk of heart attacks Make sure you tell your doctor if you have any other medical problems, especially: Keep using this medicine for the full time of treatment. Also tell them if you smoke, drink alcohol, or use illegal drugs. Do not start, stop, or change the dose of Last updated on May 16, 2023. You may report side effects to the FDA at 1-800-FDA-1088. You may report side effects to FDA at 1-800-FDA-1088. Learn about side effects, warnings, dosage, Aspirin (or other NSAIDs) sensitivity, history of or. Be sure you know how to use it. These could be symptoms of meningitis. All rights reserved. Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID) used to treat mild-to-moderate pain, and helps to relieve symptoms of arthritis (eg, osteoarthritis or rheumatoid arthritis), such as inflammation, swelling, stiffness, and joint pain. NOTE: This medicine is only for you. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This medicine may raise the risk of heart and blood vessel problems like heart attack and stroke. Follow all instructions closely. Stomach ulcers or bleeding, history of or. Do not increase your dose or use this drug more often or for longer than prescribed. health information, we will treat all of that information as protected health If you think you have become pregnant while using the medicine, tell your doctor right away. Available for Android and iOS devices. Ask your doctor if you should use sunscreen along with this medication. Side effects such as stomach upset, nausea, or ulcers may be more likely to occur. There may be drug take-back programs in your area. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Ask your doctor about any risk. You could have more side effects. Signs of kidney problems like unable to pass urine, change in how much urine is passed, blood in the urine, or a big weight gain. You should not use this medicine if you are allergic to diclofenac (Voltaren, Cataflam, Flector, and others), or if you have ever had an asthma attack or severe allergic reaction after taking aspirin or an NSAID. Do not use this medicine just before or after heart bypass surgery (coronary artery bypass graft, or CABG). However, many people have no side effects or only have minor side effects. You may also report side effects at https://www.fda.gov/medwatch. information highlighted below and resubmit the form. This effect can happen at any time while using this drug but is more likely if you use it for a long time. If you notice any of the following rare but very serious side effects, stop using this medication and get medical help right away: stomach/abdominal pain that doesn't go away, black/bloody stools, vomit that looks like coffee grounds. Diclofenac sodium gel, 3% should not be applied to open skin wounds, infections, or exfoliative dermatitis. Nonsteroidal anti-inflammatory drugs are widely used to provide pain relief, whether from osteoarthritis, rheumatoid arthritis, muscle sprain or strain or even severe menstrual cramps. The rash may be red or purple and then turn into blisters or peeling of the skin. Call your doctor for medical advice about side effects. Review/update the We're empowering you to make wise decisions about your own health, by providing you with essential health information about both medical and alternative treatment options. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. Drug information provided by: Merative, Micromedex. This is a decision you and your doctor will make. Diclofenac (Solaraze, Voltaren) topical gel is a prescription medication used to treat osteoarthritis pain and actinic keratoses. The effects of diclofenac sodium on the kidneys were studied during 4 1/2 hours in eight patients with normal renal function. Blood and urine tests may be needed to check for unwanted effects. Be ready to tell or show what was Although not all of these side effects may occur, if they do occur they may need medical attention. Unlike other erectile dysfunction treatments, Eroxon is a gel and doesn't require a doctor's prescription. Check with your information and will only use or disclose that information as set forth in our notice of Use it as directed on the prescription label at the same time every day. This medicine may raise your risk of having a heart attack or stroke. This will allow your doctor to see if the medicine is working properly and to decide if you should continue to take it. Using alcohol or tobacco with certain medicines may also cause interactions to occur. COMMON BRAND NAME(S): DICLOVIX, INFLAMMA-K, PENNSAID, PROFINAC, VOPAC MDS, Xrylix II. Dosage forms: topical cream (1%), topical gel (1%; 3%), topical kit (1%), topical solution (1.5%; 2%) Copyright: Merative US L.P. 1973, 2023. Do not use more than told. If you miss a dose of this medicine, take it as soon as possible. Do not freeze. Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. The short answer to this question is, it depends. Check with your doctor right away if you have black, tarry stools, blistering, peeling, or loosening of the skin, chest pain, chills, cough, diarrhea, fever, itching, joint or muscle pain, painful or difficult urination, red irritated eyes, red skin lesions, sore throat, sores, ulcers, or white spots in the mouth or on the lips, swollen glands, unusual bleeding or bruising, or unusual tiredness or weakness. Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID). If you do get the medication in those areas, flush with plenty of water. If you have an allergy to diclofenac or any other part of diclofenac gel (1%). Keep out of the reach of children and pets. You should not use this medication after 30 weeks of pregnancy. Call your doctor for medical advice about side effects. Kidney disease, severeShould not be used in patients with these conditions. WebDiclofenac sodium gel, 3% should be used with caution in patients with active gastrointestinal ulceration or bleeding and severe renal or hepatic impairments. Tell your doctor right away if you have any serious side effects, including: signs of kidney problems (such as change in the amount of urine), symptoms of heart failure (such as swelling ankles/feet, unusual tiredness, unusual/sudden weight gain). diclofenac heart disease, high blood pressure, high cholesterol, diabetes, or if you smoke; stomach ulcers, bleeding in your stomach or intestines; Diclofenac can affect ovulation and it may be harder to get pregnant while you are using this medicine. Wash your hands before and after use. Mayo Clinic on Incontinence - Mayo Clinic Press, Mayo Clinic on Hearing and Balance - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press, Burning, itching, redness, skin rash, swelling, or soreness at the application site, increased sensitivity of the skin to sunlight, pain or tenderness around the eyes and cheekbones, skin rash other than at the application site, ulcers or sores on the skin, other than at the application site, sores, ulcers, or white spots on lips or in mouth, burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings. Common side effects of diclofenac topical may include: heartburn, gas, stomach pain, nausea, vomiting; skin redness, itching, dryness, scaling, or peeling where the medicine was applied. They are well known to irritate the digestive tract and cause ulcers. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Do not take by mouth. Do not store in a bathroom. Medications like ibuprofen (Advil, Motrin IB) and naproxen (Aleve) are available over the counter, but you might get a prescription for drugs such as celecoxib (Celebrex), diclofenac (Cataflam, Voltaren) or meloxicam (Mobic), to name just a few. It may also be helpful to note of how often your migraine attacks occur and how much medicines you use. Ask your doctor or pharmacist about how much alcohol you may safely drink. Seal the mixture in a bag or container. This medicine is not approved for use in children. Using too much of Cambia or any other migraine medicines (eg, ergotamine, triptans, opioids, NSAIDs, or a combination treatment for 10 or more days per month) may worsen your headache. Some possible warning signs of serious side effects that can occur during treatment with this medicine may include black, tarry stools, decreased urination, severe stomach pain, skin rash, swelling of the face, fingers, feet, or lower legs, unusual bleeding or bruising, unusual weight gain, vomiting of blood or material that looks like coffee grounds, or yellow skin or eyes. Copyright: Merative US L.P. 1973, 2023. Allergy to bovine proteinZipsor capsule contains gelatin and should not be used in patients with this condition. Do not take other medications that contain aspirin, ibuprofen, or naproxen with this medication. These could be symptoms of a serious kidney problem. Appropriate studies have not been performed on the relationship of age to the effects of diclofenac in the pediatric population. You may report side effects to Health Canada at 1-866-234-2345. These side effects may go away during treatment as your body adjusts to the medicine. Diclofenac is a prescription drug that is classified as part of the non-steroidal anti-inflammatory drug (NSAID) class of medications. If you are a Mayo Clinic patient, this could Terry is one of the country's leading authorities on the science behind folk remedies. Adults50 milligrams (mg) 2 or 3 times a day, or 75 mg two times a day. Gently apply enough medication to cover the affected skin well as directed by your doctor, usually 2 times daily. WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Older adults may be at greater risk for stomach/intestinal bleeding, kidney problems, heart attack, and stroke while using this drug. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. All rights reserved. These problems can happen without warning signs. include protected health information. health information, we will treat all of that information as protected health Use your next dose at the normal time. Keep all medications away from children and pets. Visit your care team for regular checks on your progress. Voltaren-XR Zipsor Zorvolex Descriptions Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID) used to treat mild-to-moderate pain, and helps to relieve The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Brand names: Diclozor, Voltaren Follow your doctor's orders or the directions on the label. This medicine may raise the chance of severe and sometimes deadly stomach or bowel problems like ulcers or bleeding. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. You must check WebThe effects of diclofenac sodium on the kidneys were studied during 4 1/2 hours in eight patients with normal renal function. Only a very small amount of the drug gets into the bloodstream, so it may be safe for your Problems are more likely to occur if you are dehydrated, have heart failure or kidney disease, are an older adult, or if you take certain medications (see also Drug Interactions section). All rights reserved. Talk with your doctor. Along with its needed effects, a medicine may cause some unwanted effects. Generic name: Diclofenac Gel (1%) [dye-KLOE-fen-ak] In Canada - Call your doctor for medical advice about side effects. Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Diclofenac: 7 things you should know - Drugs.com Stroke, history ofUse with caution. NSAIDs like diclofenac gel (1%) may affect egg release (ovulation) in women. This medication is for use on the skin only. Talk to your care team if you are pregnant before taking this medication. Use diclofenac gel (1%) as ordered by your doctor. Children younger than 12 years of ageUse and dose must be determined by your doctor. WebDrugs and Supplements Diclofenac (Topical Application Route) Proper Use Drug information provided by: Merative, Micromedex Keep using this medicine for the full time of treatment. Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of Zipsor capsules in children 12 to 17 years of age. Data sources include IBM Watson Micromedex (updated 5 June 2023), Cerner Multum (updated 25 June 2023), ASHP (updated 11 June 2023) and others.
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